Job Description
The Senior Bioinformatics Research Scientist performs data analysis, data visualization, statistical analysis, experimental design, database development, mathematical modeling, and novel method development. Provides bioinformatics analysis for investigators and communicates analytical process and results.
Bioinformatics/Data Science Position-Center for Pediatric Neurological Disease Research, St. Jude Pediatric Translational Neuroscience Initiative, St. Jude Children’s Research Hospital, Memphis, TN.
St. Jude Children’s Research Hospital has established an expansive and multicomponent initiative in translational neuroscience with a mission to understand and treat catastrophic childhood neurological disease. This new initiative integrates basic and clinical neuroscience and partners with industry and foundations to develop and implement novel therapies. A key component of this enterprise is the Genomics Medicine Initiative (GEMINI) an individualized gene-targeted therapeutics program. The initial focus of GEMINI is on the use of antisense oligo nucleotides (ASOs) to treat monogenic catastrophic pediatric neurogenetic disorders with high unmet need.
We are seeking an individual with bioinformatics and genetics expertise and a strong working knowledge of ASO design and application to address disease mutations in the context of patient specific genomes. This individual will leverage available state-of-the-art tools and technology to enhance existing capabilities in therapeutic ASO development for neurogenetic disease.
The research environment at St. Jude is outstanding. Investigators have access to cutting edge institutional shared resources, which support broad research endeavors and includes computational biology, genomics, proteomics, CRISPR-based genome editing, mouse modeling, iPSC disease modelling, cell sorting, live cell imaging, spatial and single cell omics modalities, and advanced image acquisition, processing and analysis, amongst a variety of other specific departmental research infrastructures. There are many opportunities for collaborative interactions with world-class basic science and clinical investigators.
St Jude Children’s Research Hospital is a private, not-for-profit institute that is internationally recognized for its commitment to performing cutting edge research and providing state of the art clinical services, with the goal to improve the outcome for children with catastrophic diseases.
Job Responsibilities:
Minimum Education and/or Training:
Minimum Experience:
Special Skills, Knowledge and Abilities:
Compensation
In recognition of certain U.S. state and municipal pay transparency laws, St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets, experience and training, licensure and certifications, and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $104,000 - $186,160 per year for the role of Senior Bioinformatics Research Scientist - Center for Pediatric Neurological Disease Research.Explore our exceptional benefits!
Diversity, Equity and Inclusion
St. Jude Children’s Research Hospital has a diverse, global patient population and workforce, built on the principles of diversity, equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the world—regardless of race, religion or a family’s ability to pay. Learn more about our history and commitment.
Today, we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally, we believe our legacy of diversity, equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization, we strive to ensure the St. Jude culture, leadership approaches and talent processes are equitable and culturally responsive. View our Diversity, Equity and Inclusion Report to learn about the hospital’s roots in diversity, equity and inclusion, where we are today and our aspirations for an even better future.
St. Jude is an Equal Opportunity Employer
No Search Firms
St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
St. Jude Children's Research Hospital® was founded in 1962 by philanthropist and performer Danny Thomas. It is the first and only National Cancer Institute-designated Comprehensive Cancer Center dedicated solely to children. Since its opening, St. Jude has strived to advance cures for children with cancer and other catastrophic diseases through research and treatment. As one of the largest pediatric oncology centers in the world, St. Jude Children’s Research Hospital has treated children from all 50 states and around the world. Today, St. Jude has one of the world's leading pediatric brain tumor programs, as well as one of the largest bone marrow transplant and sickle cell disease programs in the United States. Headquartered in Memphis, Tennessee, St. Jude has eight affiliate clinics across the United States. The hospital also shares its breakthroughs with resources like St. Jude Cure4Kids and St. Jude Cloud, which enable doctors and scientists across the globe to access St. Jude findings, helping them save even more lives. Aligned with Danny Thomas’ vision, St. Jude is committed to ensuring no child is denied treatment based on race, religion, or financial standing. This is largely made possible by the American Lebanese Syrian Associated Charities® (ALSAC®), the hospital’s awareness and fundraising organization. ALSAC focuses on connecting with donors and spreading awareness about the organization while St. Jude focuses on improving survival rates through innovative, cutting-edge research and technology. Major goals of this research include understanding the molecular, genetic and chemical bases of catastrophic diseases in children, as well as finding new life-saving treatments and methods of prevention for said diseases. To learn more about St. Jude Children’s Research Hospital and its lifesaving mission, visit https://www.stjude.org.
