Job Description
A postdoctoral position is available for highly motivated individuals with a background in Computational Neuroscience to analyze complex time-series data from ongoing 2-photon microscopy experiments and animal behavior studies.
Our laboratory conducts 2-photon laser-scanning microscopy imaging of neuronal activity in awake mice, with a focus on mouse models of genetic risks for developing schizophrenia. Preference will be given to applicants who have received their Ph.D. degrees in computational neuroscience, physics, mathematics, computer science, or related fields within the last 3 years and have experience in computational neuroscience and data mining using machine learning methods.
The successful candidate will lead an independent research project dedicated to identifying abnormal neuronal activities in circuits of murine models of 22q11.2 and 3q29 deletion syndromes, two rare conditions that confer the highest genetic risks of schizophrenia.
Qualifications:
PhD in computational neuroscience, physics, mathematics, computer science, or related fields
Demonstrated hands-on experience with machine learning techniques
Strong programming skills (Python preferred)
Experience analyzing time-series data, preferably from neuroimaging or behavioral studies
Knowledge of signal processing and statistical analysis
Excellent communication skills and ability to work in a collaborative environment
Preference will be given to applicants who have a strong background in leveraging cutting-edge AI and machine-learning techniques to solve complex problems in Neuroscience. The candidate also will benefit from an outstanding, highly collaborative work environment in which a diverse team of researchers is focusing efforts toward understanding the mechanisms of schizophrenia and other psychiatric disease behaviors at the levels of neural circuits and individual neurons, synapses, and molecules.
The laboratory is equipped with two dedicated 2-photon mesoscopes (Thorlabs) and Mini-2p (Thorlabs). The successful candidate will join a diverse team of researchers whose efforts are directed toward understanding behavior at the levels of neural circuits, individual neurons, synapses, and molecules. The laboratory is part of the Department of Developmental Neurobiology, which houses specialized departmental shared resources, including an integrated support structure for rodent behavior testing, 3-dimensional brain organoids, in vivo and ex vivo cellular imaging, bioinformatics, production of genetically engineered animal models, single-cell profiling, and advanced image processing and analysis. In addition, numerous institutional shared resources and core facilities support the laboratory by providing expertise and state-of-the-art technologies.
St. Jude Children’s Research Hospital offers an excellent salary and benefits package and is an equal opportunity employer. Interested applicants should send their CVs and the names and addresses of 3 references to:Stanislav Zakharenko, M.D., Ph.D.Department of Developmental Neurobiology, MS 322
St. Jude Children’s Research Hospital262 Danny Thomas PlaceMemphis, TN 38105
St. Jude is an Equal Opportunity Employer
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St. Jude Children's Research Hospital® was founded in 1962 by philanthropist and performer Danny Thomas. It is the first and only National Cancer Institute-designated Comprehensive Cancer Center dedicated solely to children. Since its opening, St. Jude has strived to advance cures for children with cancer and other catastrophic diseases through research and treatment. As one of the largest pediatric oncology centers in the world, St. Jude Children’s Research Hospital has treated children from all 50 states and around the world. Today, St. Jude has one of the world's leading pediatric brain tumor programs, as well as one of the largest bone marrow transplant and sickle cell disease programs in the United States. Headquartered in Memphis, Tennessee, St. Jude has eight affiliate clinics across the United States. The hospital also shares its breakthroughs with resources like St. Jude Cure4Kids and St. Jude Cloud, which enable doctors and scientists across the globe to access St. Jude findings, helping them save even more lives. Aligned with Danny Thomas’ vision, St. Jude is committed to ensuring no child is denied treatment based on race, religion, or financial standing. This is largely made possible by the American Lebanese Syrian Associated Charities® (ALSAC®), the hospital’s awareness and fundraising organization. ALSAC focuses on connecting with donors and spreading awareness about the organization while St. Jude focuses on improving survival rates through innovative, cutting-edge research and technology. Major goals of this research include understanding the molecular, genetic and chemical bases of catastrophic diseases in children, as well as finding new life-saving treatments and methods of prevention for said diseases. To learn more about St. Jude Children’s Research Hospital and its lifesaving mission, visit https://www.stjude.org.
