Introduction:

Pioneering Intelligence (PI) is the newest business unit within Flagship Pioneering, focusing on inventing and building AI/ML and tech-based platform companies that transform innovation, productivity and outcome across therapeutic and non-therapeutic applications. PI is at the forefront of both technological innovation in AI/ML, and company origination that translates technology into value-creating platforms.

Position Summary: 

We are seeking a highly motivated and innovative individual to join our team as AI/ML and tech-focused Principal on the origination team. The individual will guide a team of associates to ideate/research/refine novel venture hypotheses, develop the business case and drive new company origination, and provide strategic / operational / technical oversight to early-stage companies. A successful candidate will have a strong entrepreneurial drive, a clear understanding of the operational aspects of AI/ML solutions, and a keen business and strategy acumen for AI/ML-driven value creation.

Key Responsibilities:

Venture Hypothesis Ideation:

• Oversee multiple Flagship-model explorations, guiding associates to rapidly ideate interesting areas of innovation where AI/ML can create outsized impact, and develop novel, actionable and high value venture hypotheses
• Pressure-test assumptions, value pools, technical choices, proof-of-concept results and competitive landscape, to iteratively solidify venture hypotheses with associates
• Guide team to de...